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中文名称英文名称CAS 编号规格目录价所属品牌订货号
氟西汀盐酸盐Fluoxetine hydrochloride56296-78-710MG¥790.00SIGMAF132
氟西汀盐酸盐Fluoxetine hydrochloride56296-78-750MG¥3,250.00SIGMAF132
氟西汀盐酸盐Fluoxetine hydrochloride56296-78-71G¥23,900.00SIGMAF132
品牌SIGMA
产品名称 氟西汀盐酸盐 : Fluoxetine hydrochloride ——【产品编号:SIGMA-F132】
CAS编号56296-78-7
别名盐酸氟西汀,(±)-N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride,LY-110,140 hydrochloride,Prozac
级别科学级
纯度&分析Solid,≥98 %,TLC
Tips选择性羟色胺再摄取抑制剂,抗抑郁剂。
分子式 C17H18F3NO · HCl
分子量345.79
储存条件常温避光保存。
性质
form   solid
color   white
solubility   H2O: soluble4 mg/mL
  DMSO: >5 mg/mL
原产地美国
描述

Biochem/physiol Actions

Selective serotonin reuptake inhibitor; antidepressant.

Legal Information

Sold under license from Eli Lilly and Company.

Prozac is a registered trademark of Eli Lilly and Co.

供货状态True
参考文献

Platelet-derived growth factor and reactive oxygen species (ROS) regulate Ras protein levels in primary human fibroblasts via ERK1/2. Amplification of ROS and Ras in systemic sclerosis fibroblasts. Svegliati S, et. al. J. Biol. Chem., 36474-82, (2005)

The serotonin transporter (SLC6A4) is present in B-cell clones of diverse malignant origin: probing a potential anti-tumor target for psychotropics. Meredith EJ, et. al. FASEB J., 1187-9, (2005)

Desvenlafaxine succinate: A new serotonin and norepinephrine reuptake inhibitor. Deecher DC, Beyer CE, Johnston G, Bray J, Shah S, Abou-Gharbia M, Andree TH J. Pharmacol. Exp. Ther., 657-65, (2006)

Characterization of single channel currents from primary cilia of renal epithelial cells. Raychowdhury MK, McLaughlin M, Ramos AJ, Montalbetti N, Bouley R, Ausiello DA, Cantiello HF J. Biol. Chem., 34718-22, (2007)

Lipid bodies are reservoirs of cyclooxygenase-2 and sites of prostaglandin-E2 synthesis in colon cancer cells. Accioly MT, et. al. Cancer Res., 1732-40, (2008)

Local suppression of Epstein-Barr virus (EBV)-specific cytotoxicity in biopsies of EBV-positive Hodgkin's disease. Frisan T, et. al. Blood, 1493-501, (2008)

AQP2 exocytosis in the renal collecting duct -- involvement of SNARE isoforms and the regulatory role of Munc18b. Procino G, Barbieri C, Tamma G, De Benedictis L, Pessin JE, Svelto M, Valenti G J. Cell Sci., 2097-106, (2008)

Chronic fenfluramine administration increases plasma serotonin (5-hydroxytryptamine) to nontoxic levels. Zolkowska D, Baumann MH, Rothman RB J. Pharmacol. Exp. Ther., 791-7, (2008)

Novel Control By The CA3 Region Of The Hippocampus On Neurogenesis In The Dentate Gyrus Of The Adult Rat. Liu, J.X., et al. PLoS ONE 6, e17562, (2011)

Prozac (fluoxetine, Lilly 110140), the first selective serotonin uptake inhibitor and an antidepressant drug: twenty years since its first publication. Wong, D.T., et al. Life Sci. 57, 411-441, (1995)

Blockage of 5HT2C serotonin receptors by fluoxetine (Prozac). Ni, Y.G., et al. Proc. Natl. Acad. Sci. U. S. A. 94, 2036-2040, (1997)

Potentiation of the fluoxetine-induced increase in dialysate levels of serotonin (5-HT) in the frontal cortex of freely moving rats by combined blockade of 5-HT1A and 5-HT1B receptors with WAY 100,365 and GR 127,935. Gobert, A., et al. J. Neurochem. 68, 1159-1163, (1997)

Merck 14,4185

类型BSZH 生物化学研究
安全信息
符号  GHS05GHS07GHS09
信号词  Danger
危险声明  H302-H318-H400
警示性声明  P273-P280-P305 + P351 + P338
个人防护装备  dust mask type N95 (US), Eyeshields, Faceshields, Gloves
危害码 (欧洲)  Xn,N
风险声明 (欧洲)  22-41-50
安全声明 (欧洲)  26-39-61
WGK德国  3
RTECS  UI4050000