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中文名称英文名称CAS 编号规格目录价所属品牌订货号
孕酮Progesterone57-83-05G450.00BSZHP54372
孕酮Progesterone57-83-025G1,160.00BSZHP54372
孕酮Progesterone57-83-0100G4,300.00BSZHP54372
孕酮Progesterone57-83-01KG32,100.00BSZHP54372
品牌BSZH
产品名称 孕酮 : Progesterone ——【产品编号:BSZH-P54372】
CAS编号57-83-0
别名黄体酮,孕烯二酮,黄体素,4-孕甾烯-3,20-二酮,孕激素,4-Pregnene-3,20-dione
级别细胞培养级
纯度&分析≥99.5%,powder, BioReagent, suitable for cell culture
Tips诱发子宫内壁的成熟和分泌活性,抑制排卵。孕酮(黄体酮)和乳腺癌的发生有密切关系。
分子式 C21H30O2
分子量314.46
储存条件常温避光保存。
性质
description synthesized from materials derived from plant source
product line BioReagent
form powder
potency 0.1-20 ng/mL
mp 128-132 °C(lit.)
solubility absolute ethanol: soluble1 mg/mL
suitability suitable for cell culture
原产地美国
描述

Application

Use in cell culture applications to study sterol regulation of cell signaling and gene expression.

Other Notes

由卵巢黄体产生的类固醇激素。

Reconstitution

To prepare 20μg/ml stock solution, add 1ml absolute ethanol per mg progesterone, gently swirl to dissolve, add 49ml sterile medium per ml ethanol.

Physical form

powder-RT; stock-frozen in working aliquots, avoid repeated freeze/thaw.

Biochem/physiol Actions

诱导子宫内皮细胞的成熟和分泌活动;抑制排卵。孕酮与乳腺癌的病因有关。

供货状态True
参考文献

Kadegowda, A.K., et al., Peroxisome proliferator-activated receptor-gamma activation and long-chain fatty acids alter lipogenic gene networks in bovine mammary epithelial cells to various extents. J. Dairy Sci. 92, 4276-89, (2009)

Hu, H., et al., In vitro culture and characterization of a mammary epithelial cell line from Chinese Holstein dairy cow. PLoS ONE 4, 7636, (2009)

Koito, H., and Li, J., Preparation of rat brain aggregate cultures for neuron and glia development studies. J. Vis. Exp. , (2009)

Heikkila, O., et al., Internalization of Coxsackievirus A9 Is Mediated by {beta}2-Microglobulin, Dynamin, and Arf6 but Not by Caveolin-1 or Clathrin J. Virol. 84, 3666-81, (2010)

Blackmore, M.G., et al., High content screening of cortical neurons identifies novel regulators of axon growth. Mol. Cell. Neurosci. 44, 43-54, (2010)

Heikkilä, O., et al., Internalization Of Coxsackievirus A9 Is Mediated By β2-Microglobulin, Dynamin, And Arf6 But Not By Caveolin-1 Or Clathrin J. Virol. 84, 3666-3681, (2010)

El-Maarri, O., et al., Methylation At Global LINE-1 Repeats In Human Blood Are Affected By Gender But Not By Age Or Natural Hormone Cycles. PLoS ONE 6, e16252, (2011)

Kinoshita, K., et al., Long-Term Monitoring Of Fecal Steroid Hormones In Female Snow Leopards (Panthera Uncia) During Pregnancy Or Pseudopregnancy. PLoS ONE 6, e19314, (2011)

Qiu, M., and Lange, C.A., MAP kinases couple multiple functions of human progesterone receptors: degradation, transcriptional synergy, and nuclear association. J. Steroid Biochem. Mol. Biol. 85, 147-157, (2003)

Lanari, C., and Molinolo, A.A., Progesterone receptors--animal models and cell signalling in breast cancer. Diverse activation pathways for the progesterone receptor: possible implications for breast biology and cancer. Breast Cancer Res. 4, 240-243, (2002)

Anderson, E., The role of oestrogen and progesterone receptors in human mammary development and tumorigenesis. Breast Cancer Res. 4, 197-201, (2002)

Albrecht, E.D., and Pepe, G.J., Steroid hormone regulation of angiogenesis in the primate endometrium. Front. Biosci. 8, 416-429, (2003)

Rider, V., Progesterone and the control of uterine cell proliferation and differentiation. Front. Biosci. 7, 1545-1555, (2002)

Merck 14,7773

Beil. 7,IV,2395

类型BSZH 生物化学研究
安全信息
符号 GHS08
信号词 Warning
危险声明 H351
警示性声明 P281
个人防护装备 Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
危害码 Xn
风险声明 40
安全声明 36/37
WGK德国 3
RTECS TW0175000