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中文名称英文名称CAS 编号规格目录价所属品牌订货号
氯霉素Chloramphenicol56-75-75G170.00SIGMAC0378
氯霉素Chloramphenicol56-75-725G486.00SIGMAC0378
氯霉素Chloramphenicol56-75-7100G1,530.00SIGMAC0378
氯霉素Chloramphenicol56-75-7500G4,950.00SIGMAC0378
氯霉素Chloramphenicol56-75-71KG8,860.00SIGMAC0378
品牌SIGMA
产品名称 氯霉素 : Chloramphenicol ——【产品编号:SIGMA-C0378】
CAS编号56-75-7
别名左旋霉素,左霉素,Chloromycetin
级别科学级
纯度&分析≥98% (TLC)
Tips一种常用的研究级抗生素类制品,适用于科学研究、辅料、规模化生产等。
分子式Cl2CHCONHCH(CH2OH)CH(OH)C6H4NO2
分子量323.13
储存条件常温避光保存。
性质
Appearance (Color) White to Off-White
Appearance (Form) Powder
Solubility (Color) Colorless to Light Yellow
Solubility (Turbidity) Clear
  50 mg/ml, EtOH
Infrared spectrum Conforms to Structure
Carbon 39.9 - 41.9 %
Nitrogen 8.5 - 8.8 %
Purity (TLC) ≥98 %
原产地美国
描述

Application

Used as a seletion agent for transformed cells containing chloramphenicol resistance genes.

Biochem/physiol Actions

Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition). Bacteriostatic.
Mode of Resistance: Acetylation by chloramphenicol acetyltransferase (cat gene).

供货状态True
参考文献

Wayne, K.J., et al., Localization And Cellular Amounts Of The WalRKJ (VicRKX) Two-component Regulatory System Proteins In Serotype 2 Streptococcus Pneumoniae. J. Bacteriol. 192, 4388-94, (2010)

Wolfenden, R.E., et al., Development And Evaluation Of Candidate Recombinant Salmonella-vectored Salmonella Vaccines. Poult. Sci. 89, 2370-9, (2010)

Merck 14,2077

Beil. 13,IV,2742

Aldrich MSDS 1, 364:D / Corp MSDS 1 (1), 722:C / FT-IR 2 (2), 2987:A / FT-IR 1 (2), 362:D / FT-NMR 1 (2), 1380:A / IR-Spectra (3), 1074:A / IR-Spectra (2), 939:D / NMR-Reference 2 (2), 340:B / RegBook 1 (2), 2011:G / Sax 6, 668 / Sigma FT-IR 1 (1), 634:C / Structure Index 1, 321:A:2

类型抗生素
安全信息
符号 GHS08
信号词 Danger
危险声明 H350
警示性声明 P201-P308 + P313
个人防护装备 Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
危害码 T
风险声明 45
安全声明 53-45
WGK德国 3
RTECS AB6825000