» 产品价格(Market Price)⇒ 联系客服 +
中文名称英文名称CAS 编号规格目录价所属品牌订货号
苯胺Aniline62-53-3500ML575.00SIGMA-ALDRICH132934
苯胺Aniline62-53-32.5L1,726.00SIGMA-ALDRICH132934
苯胺Aniline62-53-310L4,355.00SIGMA-ALDRICH132934
苯胺Aniline62-53-325L9,520.00SIGMA-ALDRICH132934
品牌SIGMA-ALDRICH
产品名称 苯胺 : Aniline ——【产品编号:SIGMA-ALDRICH-132934】
CAS编号62-53-3
别名阿尼林,阿尼林油,胺基苯,氨基苯
级别特优级
纯度&分析ReagentPlus®, 99%
TipsBSZH品质推荐:SIGMA-ALDRICH 进口高等级基础试剂,多重遴选,国际标准严苛测试,全球化学产品质量标杆,满足用户更高应用要求。 使用SIGMA-ALDRICH品质优异、表现卓越的试剂类产品,将有助于使您的研究项目更早获益。
分子式C6H5NH2
分子量93.13
储存条件常温避光保存。
性质
grade ReagentPlus®
vapor density 3.22 (185 °C, vs air)
vapor pressure 0.7 mmHg ( 25 °C)
assay 99%
autoignition temp. 1139 °F
expl. lim. 11 %
color APHA: ≤250
refractive index n20/D 1.586(lit.)
bp 184 °C(lit.)
mp −6 °C(lit.)
density 1.022 g/mL at 25 °C(lit.)
原产地美国
描述

Biochem/physiol Actions

The acute toxicity of aniline involves its activation in vivo to 4-hydroxyaniline and the formation of adducts with hemoglobin. In erythrocytes, this is associated with the release of iron and the accumulation of methemoglobin and the development of hemolytic anemia and inflammation of the spleen. Tumor formation is often observed in the spleen on prolonged administration.

 

Physical properties

材料在储存期间颜色变暗,成为红棕色,但纯度不会受到​影响。

法律信息

ReagentPlus 注册商标 Sigma-Aldrich Co. LLC

供货状态True
参考文献

High-Density Real-Time PCR-Based in vivo Toxicogenomic Screen to Predict Organ-Specific Toxicity. Gabriella Fabian et al Int. J. Mol. Sci. 12, 6116-34, (2011)

Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Giulia Caron et al J. Med. Chem. 48, 3269-79, (2005)

QSAR study on permeability of hydrophobic compounds with artificial membranes. Masaaki Fujikawa et al Bioorg. Med. Chem. 15, 3756-67, (2007)

The many roles for fluorine in medicinal chemistry. William K Hagmann et al J. Med. Chem. 51, 4359-69, (2008)

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Lourdes Santana et al J. Med. Chem. 51, 6740-51, (2008)

Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins. Alfonso Pérez-Garrido et al Bioorg. Med. Chem. 17, 896-904, (2009)

Aryl H-phosphonates 17: (N-aryl)phosphoramidates of pyrimidine nucleoside analogues and their synthesis, selected properties, and anti-HIV activity. Joanna Romanowska et al J. Med. Chem. 54, 6482-91, (2011)

QSAR study and synthesis of new phenyltropanes as ligands of the dopamine transporter (DAT). Sylvie Mavel et al Bioorg. Med. Chem. 20, 1388-95, (2012)

Biomonitoring of aromatic amines VI: determination of hemoglobin adducts after feeding aniline hydrochloride in the diet of rats for 4 weeks. Zwirner-Baier, I., et al. Arch. Toxicol. 77, 672-67, (2003)

Hemolytic drugs aniline and dapsone induce iron release in erythrocytes and increase the free iron pool in spleen and liver. Ciccoli, L., et al. Toxicol. Lett. 110, 57-66, (1999)

Merck 14,659

Beil. 12,IV,223

Fieser 6,21

Aldrich MSDS 1, 125:D / Corp MSDS 1 (1), 270:A / FT-IR 1 (1), 1189:A / FT-IR 2 (2), 2024:A / FT-NMR 1 (2), 451:A / IR-Spectra (2), 630:A / IR-Spectra (3), 714:A / NMR-Reference 2 (1), 987:A / RegBook 1 (1), 1383:A / Sax 6, 280 / Sigma FT-IR 1 (2), 284:A / Structure Index 1, 214:A:1 / Vapor Phase 3, 1109:A

类型BSZH 高等级基础试剂
安全信息
符号 GHS05GHS06GHS08GHS09 
信号词 Danger
危险声明 H301-H311-H317-H318-H331-H341-H351-H372-H400
警示性声明 P261-P273-P280-P301 + P310-P305 + P351 + P338-P311
个人防护装备 Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
危害码 (欧洲) T,N
风险声明 (欧洲) 23/24/25-40-41-43-48/23/24/25-50-68
安全声明 (欧洲) 26-27-36/37/39-45-46-61-63
RIDADR UN 1547 6.1/PG 2
WGK德国 2
RTECS BW6650000
燃点(华氏) 158 °F
燃点(摄氏) 70 °C