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中文名称英文名称CAS 编号规格目录价所属品牌订货号
盐酸美加明Mecamylamine hydrochloride826-39-15MG490.00SIGMAM9020
盐酸美加明Mecamylamine hydrochloride826-39-125MG1,980.00SIGMAM9020
盐酸美加明Mecamylamine hydrochloride826-39-1100MG5,990.00SIGMAM9020
盐酸美加明Mecamylamine hydrochloride826-39-11G33,520.00SIGMAM9020
品牌SIGMA
产品名称 盐酸美加明 : Mecamylamine hydrochloride ——【产品编号:SIGMA-M9020】
CAS编号826-39-1
别名盐酸美卡拉明,美卡拉明盐酸盐,美加明盐酸盐,异坎胺,2-(Methylamino)isocamphane hydrochloride,Inversine,N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine hydrochloride
级别科学级
纯度&分析≥98.0%
Tips非竞争性的烟碱型乙酰胆碱受体拮抗剂。
分子式C11H21N · HCl
分子量203.75
储存条件常温避光保存。
性质
solubility ethanol: soluble122 mg/mL
  H2O: soluble47 mg/mL
  isopropanol: soluble476 mg/mL
  glycerol: soluble95 mg/mL
原产地美国
描述

Biochem/physiol Actions

Noncompetitive nicotinic acetylcholine receptor antagonist; preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier.

Caution

Solutions are stable to autoclaving.

供货状态True
参考文献

Castillo, P.E., et al., Multiple and opposing roles of cholinergic transmission in the main olfactory bulb. J. Neurosci. 19, 9180-9191, (1999)

Damaj, M.I., et al., Pharmacological characterization of nicotine-induced seizures in mice. J. Pharmacol. Exp. Ther. 291, 1284-1291, (1999)

Panagis, G., et al., Selective c-fos induction and decreased dopamine release in the central nucleus of amygdala in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome. Synapse 35, 15-25, (2000)

Al-Zi'abi, M.O., et al., Survival Role Of Locally Produced Acetylcholine In The Bovine Corpus Luteum. Biol. Reprod. 80, 823-32, (2009)

Merck 14,5774

类型BSZH 生物化学研究
安全信息
符号 GHS06
信号词 Danger
危险声明 H301-H315-H319-H335
警示性声明 P261-P301 + P310-P305 + P351 + P338
个人防护装备 dust mask type N95 (US), Eyeshields, Faceshields, Gloves
危害码 Xn
风险声明 22-36/37/38
安全声明 36/37/39
RIDADR UN 2811 6.1/PG 3
WGK德国 3
RTECS RB6900000