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中文名称英文名称CAS 编号规格目录价所属品牌订货号
亚精胺Spermidine124-20-91G¥410.00SIGMAS2626
亚精胺Spermidine124-20-95G¥1,399.00SIGMAS2626
亚精胺Spermidine124-20-925G¥5,611.00SIGMAS2626
品牌SIGMA
产品名称 亚精胺 : Spermidine ——【产品编号:SIGMA-S2626】
CAS编号124-20-9
别名1,8-二氨基-4-氮杂辛烷,N-(3-氨基丙基)-1,4-丁二胺
级别科学级
纯度&分析≥98% (GC)
TipsInhibits neuronal nitric oxide synthase (nNOS).
分子式NH2(CH2)3NH(CH2)4NH2
分子量145.25
储存条件2-8 °C 冷藏保存。
性质
assay ≥98% (GC)
refractive index n20/D 1.479(lit.)
density 0.925 g/mL at 25 °C(lit.)
storage temp. 2-8°C
原产地美国
描述

Caution

如果需要无菌溶液,则应采用无菌过滤而非高压灭菌。时间一长,亚精胺将发生脱氨基作用;溶液应采用冷冻保存。通常需要配制新溶液。

包装

1, 5, 25 g in glass btl

Biochem/physiol Actions

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.

供货状态True
参考文献

Warf, M.B., et al., Pentamidine reverses the splicing defects associated with myotonic dystrophy. PLoS Pathog. 106, 18551-18556, (2009)

Krug, M.S., Berger, S.L. Meth. Enzymol. 152, 321, (1987)

Hu, J., et al., Polyamines inhibit nitric oxide synthase in rat cerebellum. Neurosci. Lett. 175, 41-45, (1994)

Cull, M., and McHenry, C.S., Preparation of extracts from prokaryotes. Meth. Enzymol. 182, 147-153, (1990)

Baumann P, et al., Purification of human Rad51 protein by selective spermidine precipitation. Mutat. Res. 384, 65-72, (1997)

Tabor, C.W., Tabor, H. Annu. Rev. Biochem. 53, 749, (1984)

Bouché, J.P. Anal. Biochem. 115, 42, (1981)

Blethen, S.L. J. Biol. Chem. 243, 1671, (1968)

Wu, W.H., Morris, D.R. J. Biol. Chem. 248, 1687, (1973)

Karkas, J.D. J. Biol. Chem. 250, 8657, (1975)

Merck 14,8742

Beil. 4,IV,1300

Aldrich MSDS 1, 1616:D / Corp MSDS 1 (2), 3164:C / FT-IR 2 (1), 486:C / FT-IR 1 (1), 309:D / FT-NMR 1 (1), 501:B / IR-Spectra (3), 180:F / IR-Spectra (2), 163:C / NMR-Reference 2 (1), 266:D / RegBook 1 (1), 331:G / Sax 6, 2460 / Sigma FT-IR 1 (2), 23:C / Structure Index 1, 45:C:9

类型BSZH 生物化学研究
安全信息
符号 GHS05
信号词 Danger
危险声明 H314
警示性声明 P280-P305 + P351 + P338-P310
个人防护装备 Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
危害码 C
风险声明 34
安全声明 26-36/37/39-45
RIDADR UN 2735 8/PG 2
WGK德国 3
RTECS EJ7000000
燃点(华氏) 233.6 °F
燃点(摄氏) 112 °C