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中文名称英文名称CAS 编号规格目录价所属品牌订货号
L-异亮氨酸L-Isoleucine73-32-525G¥766.00SIGMAI7403
L-异亮氨酸L-Isoleucine73-32-5100G¥2,259.00SIGMAI7403
L-异亮氨酸L-Isoleucine73-32-51KG¥12,770.00SIGMAI7403
L-异亮氨酸L-Isoleucine73-32-55KG¥29,626.00SIGMAI7403
品牌SIGMA
产品名称 L-异亮氨酸 : L-Isoleucine ——【产品编号:SIGMA-I7403】
CAS编号73-32-5
别名(2S,3S)-2-氨基-3-甲基戊酸,L-异白氨酸,L-异闪白氨基酸,L-α-氨基-β-甲基戊酸,(2S,3S)-2-Amino-3-methylpentanoic acid,Ile,H-Ile-OH
级别药典级
纯度&分析98.5-101.0%,from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture
Tips非动物源,符合美国药典(USP)、欧洲药典(EP)及日本药典(JP)标准,可用于细胞培养等。
分子式C2H5CH(CH3)CH(NH2)CO2H
分子量131.17
储存条件常温避光保存。
性质
biological source from non-animal source
assay 98.5-101.0%
form powder
total impurities endotoxin, tested
mp 288 °C (dec.)(lit.)
solubility 1 M HCl: soluble50 mg/mL
suitability meets EP, JP, USP testing specifications
  suitable for cell culture
原产地美国
描述

The alkyl amino acid L-isoleucine is an isomer of L-leucine, differing in the position of the side chain. In L-isoleucine, the methyl group is on the b-carbon of the amino acid chain, rather than the g-carbon as in Lleucine. Isoleucine is biosynthesized from threonine through the formation of a-ketobutyrate. Isoleucine is degraded to acetyl CoA and to propionyl CoA. Isoleucine provides a source of nitrogen for transport to the liver and kidney.

The induction of apoptosis upon deprivation of isoleucine and other amino acids in two different sets of cultured cells, PC12 cells and postmitotic neurons isolated from fetal rat brains, has been studied. Isoleucine has been shown to block lysine transport in cultured chicken jejunum epithelial cells. The interaction of isoleucine with Arabidopsis thaliana threonine deaminase has been examined by biochemical and mass spectrometric studies.

A GC/MS method for the analysis of various amino acids, including isoleucine, via pyrolysis in the presence of hexamethyldisilazane has been described.

供货状态True
参考文献

Merck 14,5179

Beil. 4,IV,2775

Corp MSDS 1 (1), 2024:A / FT-IR 2 (1), 914:A / FT-IR 1 (1), 575:D / IR-Spectra (3), 344:C / IR-Spectra (2), 306:H / NMR-Reference 2 (1), 489:C / RegBook 1 (1), 657:C / Sax 6, 1643 / Sigma FT-IR 1 (1), 192:B / Structure Index 1, 97:B:1

类型氨基酸
安全信息
个人防护装备 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK德国 1