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中文名称英文名称CAS 编号规格目录价所属品牌订货号
盐酸平阳霉素BLEOCIN™ Antibiotic55658-47-410MG992.00SIGMA203408
盐酸平阳霉素BLEOCIN™ Antibiotic55658-47-4100MG6,300.00SIGMA203408
盐酸平阳霉素BLEOCIN™ Antibiotic55658-47-41G41,600.00SIGMA203408
品牌SIGMA
产品名称 盐酸平阳霉素 : BLEOCIN™ Antibiotic ——【产品编号:SIGMA-203408】
CAS编号55658-47-4
别名平阳霉素盐酸盐,BLEOCIN(TM), STREPTOMYCES VERTICILLUS,Bleomycin A5 Hydrochloride for Injection
级别科学级
纯度&分析Streptomyces verticillus, Cell Culture-Tested
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分子式C₅₇H₈₉CuN₁₉O₂₁S₂ · 3HCl
分子量1477.04
储存条件2-8 °C 冷藏保存。
性质

外观:蓝色结晶粉末
溶解性:易溶于水
用途及描述:科研试剂,广泛应用于分子生物学,药理学等科研方面。平阳霉素是由平阳链霉菌产生的博莱霉素类抗肿瘤抗生素,能抑制癌细胞DNA的合成和切断DNA链,影响癌细胞代谢功能,促进癌细胞变性,坏死。用于细胞实验,溶解后,需用一次性针头滤器过滤除菌。

form   Blue lyophilized solid
purity   ≥85% by HPLC
storage conditions   Hygroscopic
  Protect from light
  Ok to freeze
toxicity   Harmful & Carcinogenic / Teratogenic
shipped in   ambient
storage temp.   +2C to +8C

原产地美国
描述

Overview
A unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells. BLEOCIN™ Antibiotic cleaves double-stranded DNA and inhibits DNA synthesis, resulting in cell death. Can be used for selection of recombinant clones in a variety of cell types transfected with vectors containing a ble resistance marker. Copper content: ≥3.5%. Potency: ≥750 µg/mg.
A unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells. BLEOCIN™ cleaves double-stranded DNA and inhibits DNA synthesis, resulting in cell death. Can be used for selection of recombinant clones in a variety of cell types transfected with vectors containing a ble resistance marker. Copper content: ≥3.5%. Potency: ≥750 µg/mg.


Storage and Shipping Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.

供货状态True
参考文献N/A
类型抗生素
安全信息

RTECS  EC5990700
R Phrase  R: 20/21/22-36/37/38-40-42/43

Harmful by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.
Limited evidence of a carcinogenic effect.
May cause sensitization by inhalation and skin contact.
S Phrase  S: 22-26-36/37/39-45

Do not breathe dust.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).