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中文名称英文名称CAS 编号规格目录价所属品牌订货号
L-甲硫氨酸L-Methionine63-68-325G¥296.00SIGMAM5308
L-甲硫氨酸L-Methionine63-68-3100G¥844.00SIGMAM5308
L-甲硫氨酸L-Methionine63-68-31KG¥5,325.00SIGMAM5308
L-甲硫氨酸L-Methionine63-68-35KG¥16,820.00SIGMAM5308
品牌SIGMA
产品名称 L-甲硫氨酸 : L-Methionine ——【产品编号:SIGMA-M5308】
CAS编号63-68-3
别名(S)-2-氨基-4-(甲硫基)丁酸,L-2-氨基-4-(甲硫基)丁酸,L-蛋氨酸,L-2-氨基-4-甲硫基丁酸,(S)-2-Amino-4-(methylmercapto)butyric acid,L-2-Amino-4-(methylthio)butanoic acid,H-Met-OH
级别药典级
纯度&分析99.0-101.0%,from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture
Tips非动物源,符合美国药典(USP)、欧洲药典(EP)及日本药典(JP)标准,可用于细胞培养等。
分子式CH3SCH2CH2CH(NH2)CO2H
分子量149.21
储存条件常温避光保存。
性质
biological source from non-animal source
assay 99.0-101.0%
form powder
total impurities endotoxin, tested
mp 284 °C (dec.)(lit.)
solubility H2O: soluble25 mg/mL
suitability meets EP, JP, USP testing specifications
  suitable for cell culture
原产地美国
描述

Methionine is one of the common sulfur-containing amino acids. The biosynthesis of methionine initially occurs by the condensation of homoserine and succinyl-CoA via the action of homoserine
acyltransferase. Subsequently, cystathionine g-synthase displaces the succinate group with cysteine to give cystathionine. Cystathionine b-lyase then hydrolyzes cystathionine to produce homocysteine. Transfer of a methyl group from N5-methyltetrahydrofolate to the homocysteine forms methionine.

Methionine is a common methyl-group donor to various substrates, such as creatine, epinephrine, ergosterol, and choline. Methionine is a relatively hydrophobic amino acid residue, and as such is frequently buried in protein three-dimensional structure, making modification of methionine residues difficult.

供货状态True
参考文献

Benavides, M.A., et al., Suppression By L-methionine Of Cell Cycle Progression In LNCaP And MCF-7 Cells But Not Benign Cells. Anticancer Res. 30, 1881-5, (2010)

Bucak, M.N., et al., Effects Of Antioxidants On Post-thawed Bovine Sperm And Oxidative Stress Parameters: Antioxidants Protect DNA Integrity Against Cryodamage. Cornea 61, 248-53, (2010)

Anckaert, E., et al., Effects Of Low Methyl Donor Levels In Culture Medium During Mouse Follicle Culture On Oocyte Imprinting Establishment. Biol. Reprod. 83, 377-86, (2010)

Merck 14,5975

Beil. 4,IV,3189

Corp MSDS 1 (2), 2232:D / FT-IR 1 (1), 594:C / FT-IR 2 (1), 940:C / FT-NMR 1 (1), 894:A / IR-Spectra (3), 353:H / IR-Spectra (2), 314:C / NMR-Reference 2 (1), 501:B / RegBook 1 (1), 673:L / Sax 6, 1766 / Sigma FT-IR 1 (1), 204:C / Structure Index 1, 101:C:7

类型氨基酸
安全信息
个人防护装备 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK德国 1