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中文名称英文名称CAS 编号规格目录价所属品牌订货号
盐酸阿米洛利Amiloride hydrochloride hydrate17440-83-41G¥557.00SIGMAA7410
盐酸阿米洛利Amiloride hydrochloride hydrate17440-83-45G¥2,293.00SIGMAA7410
盐酸阿米洛利Amiloride hydrochloride hydrate17440-83-410G¥3,710.00SIGMAA7410
盐酸阿米洛利Amiloride hydrochloride hydrate17440-83-4100G¥25,220.00SIGMAA7410
品牌SIGMA
产品名称 盐酸阿米洛利 : Amiloride hydrochloride hydrate ——【产品编号:SIGMA-A7410】
CAS编号17440-83-4
别名阿米洛利盐酸盐,N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride hydrate
级别科学级
纯度&分析≥98% (TLC), powder
Tips有较强的保钾利尿效果,其作用部位为远曲小管和皮质的集合管。
分子式 C6H8ClN7O · HCl · xH2O
分子量266.09 (anhydrous basis)
储存条件常温避光保存。
性质
assay ≥98% (TLC)
form powder
color yellow
solubility H2O: soluble50 mg/mL, clear, yellow-green
原产地美国
描述

Caution

Protect from light.

Biochem/physiol Actions

Selective T-type calcium channel blocker and blocker of epithelial sodium channel. Selective inhibitor of urokinase plasminogen activator (uPA).

供货状态True
参考文献

Dejouvencel, T., et al., Fibrinolytic Cross-talk: A New Mechanism For Plasmin Formation. Blood 115, 2048-56, (2010)

Rumsey, J.W., et al., Tissue Engineering The Mechanosensory Circuit Of The Stretch Reflex Arc: Sensory Neuron Innervation Of Intrafusal Muscle Fibers. Biomaterials 31, 8218-27, (2010)

Almaça, J., et al., Functional Genomics Assays To Study CFTR Traffic And ENaC Function. Methods Mol. Biol. 742, 249-64, (2011)

Tang, C.M., et al., Amiloride selectively blocks the low threshold (T) calcium channel. Science 240, 213-215, (1988)

Kleyman, T.R. and Kragoe, E.J., Jr., Amiloride and its analogs as tools in the study of ion transport. J. Membr. Biol. 105, 1-21, (1988)

Jankun, J., and Skrzypczak-Jankun, E.

Molecular basis of specific inhibition of urokinase plasminogen activator by amiloride. Cancer Biochem. Biophys. 17, 109-123, (1999)

Alliegro, M.C., et al., Amiloride inhibition of angiogenesis in vitro. J. Exp. Zool. 267, 245-252, (1993)

Merck 14,406

类型BSZH 生物化学研究
安全信息
符号 GHS06
信号词 Danger
危险声明 H301
警示性声明 P301 + P310
个人防护装备 Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
RIDADR UN 2811 6.1/PG 3
WGK德国 3