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中文名称英文名称CAS 编号规格目录价所属品牌订货号
嘌呤霉素盐酸盐Puromycin dihydrochloride from Streptomyces alboniger58-58-225MG¥662.00SIGMAP7255
嘌呤霉素盐酸盐Puromycin dihydrochloride from Streptomyces alboniger58-58-2100MG¥2,350.00SIGMAP7255
嘌呤霉素盐酸盐Puromycin dihydrochloride from Streptomyces alboniger58-58-21G¥16,754.00SIGMAP7255
品牌SIGMA
产品名称 嘌呤霉素盐酸盐 : Puromycin dihydrochloride from Streptomyces alboniger ——【产品编号:SIGMA-P7255】
CAS编号58-58-2
别名嘌呤霉素二盐酸盐,盐酸嘌呤霉素,二氢氯化嘌呤毒素,3′-[α-Amino-p-methoxyhydrocinnamamido]-3′-deoxy-N,N-dimethyladenosine
级别科学级
纯度&分析≥98% (HPLC), powder
Tips一种常用的研究级抗生素类制品,来源于白色链球菌。
分子式 C22H29N7O5 · 2HCl
分子量544.43
储存条件-20 °C 低温冷冻保存。
性质
Quality Level   PREMIUM
assay   ≥98% (HPLC)
form   powder
solubility   H2O: soluble50 mg/mL (Sterilize stock solution by filtration using 0.22 μm filter then store in aliquots at −20 °C.)
storage temp.   −20°C
原产地美国
描述

Application

Recommended for use as a selection agent at a range of 1-10 μg/mL.

Biochem/physiol Actions

Nucleoside antibiotic. Protein synthesis inhibitor that causes premature chain termination by acting as an analog of the 3′-terminal end of aminoacyl-tRNA. Prevents growth of bacteria, protozoa, algae, and mammalian cells. Acts very quickly and can kill 99% of cells within 2 days, the resistance gene (puromycin acetyltransferase) gives very effective protection.

供货状态True
参考文献

Wielders, E., et al., Generation Of Double-knockout Embryonic Stem Cells. Methods Mol. Biol. 530, 205-18, (2009)

de la Luna, S., Ortin, J., pac gene as efficient dominant marker and reporter gene in mammalian cells. Meth. Enzymol. 216, 376, (1992)

Nathans, D., Gottlieb, D., Shaw, P.D. Antibiotics New York, NY , (1967) 1, 259

Merck 14,7943

Beil. 26,IV,3704

类型抗生素
安全信息
符号  GHS07
信号词  Warning
危险声明  H302
个人防护装备  dust mask type N95 (US), Eyeshields, Gloves
危害码  Xn
风险声明  22
WGK德国  3
RTECS  AU7355000