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中文名称英文名称CAS 编号规格目录价所属品牌订货号
黄嘌呤氧化酶Xanthine Oxidase from bovine milk9002-17-95UN¥684.00SIGMAX4500
黄嘌呤氧化酶Xanthine Oxidase from bovine milk9002-17-925UN¥2,320.00SIGMAX4500
黄嘌呤氧化酶Xanthine Oxidase from bovine milk9002-17-9100UN¥7,839.00SIGMAX4500
品牌SIGMA
产品名称 黄嘌呤氧化酶 : Xanthine Oxidase from bovine milk ——【产品编号:SIGMA-X4500】
CAS编号9002-17-9
别名XOD,Xanthine:oxygen,oxidoreductase
级别科学级
纯度&分析Grade III, ammonium sulfate suspension, 1.0-2.0 units/mg protein
Tips来源于牛奶。
分子式N/A
分子量N/A
储存条件2-8 °C 冷藏保存。
性质
type Grade III
form ammonium sulfate suspension
foreign activity uricase ≤0.1%
storage temp. 2-8°C
原产地美国
描述

Analysis Note

Protein determined by biuret

Biochem/physiol Actions

Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids.1,2 It plays a vital role in the metabolism of some drugs, as well as purines and pyrimidines.3 It is also known to be a biological source of reactive oxygen species.4

General description

Formerly E.C. 1.1.3.22

Preparation Note

Chromatographically purified

Unit Definition

One unit will convert 1.0 μmole of xanthine to uric acid per min at pH 7.5 at 25 °C. Approx. 50% of the activity is obtained with hypoxanthine as substrate.

Physical form

Suspension in 2.3 M (NH4)2SO4, 10 mM sodium phosphate buffer, pH 7.8, containing 1 mM EDTA and 1 mM sodium salicylate

供货状态True
参考文献

1. A. Nagao et al., Inhibition of Xanthine Oxidase by Flavonoids Biosci. Biotechnol. Biochem. 63, 1787, (1999)

2. J. Aucamp et al., Inhibition of xanthine oxidase by catechins from tea (Camellia sinensis) Anticancer Res. 17, 4381, (1997)

3. T.A. Krenitsky et al., A comparison of the specificities of xanthine oxidase and aldehyde oxidase Arch. Biochem. Biophys. 150, 585, (1972)

4. Y. Ohta et al., Xanthine oxidase-derived reactive oxygen species contribute to the development of d-galactosamine-induced liver injury in rats Free Radic. Res. 41, 135, (2007)

Hickey, C.M., et al., Mitochondrial Ca2+ Activates A Cation Current In Aplysia Bag Cell Neurons. J. Autoimmun. 103, 1543-56, (2010)

类型酶 & 辅酶
安全信息
个人防护装备 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK德国 3
RTECS RQ8455000