» 产品价格(Market Price)⇒ 联系客服 +
中文名称英文名称CAS 编号规格目录价所属品牌订货号
阿糖胞苷Cytosine β-D-arabinofuranoside147-94-4100MG300.00SIGMAC1768
阿糖胞苷Cytosine β-D-arabinofuranoside147-94-41G1,753.00SIGMAC1768
阿糖胞苷Cytosine β-D-arabinofuranoside147-94-45G7,066.00SIGMAC1768
品牌SIGMA
产品名称 阿糖胞苷 : Cytosine β-D-arabinofuranoside ——【产品编号:SIGMA-C1768】
CAS编号147-94-4
别名胞嘧啶 β-D-呋喃阿拉伯糖苷,(β-D-阿拉伯呋喃糖基)胞嘧啶,Ara-C,胞嘧啶阿拉伯糖苷,阿拉伯糖胞嘧啶,阿糖胞嘧啶
级别科学级
纯度&分析crystalline
Tips一种常见的核酸类衍生物。
分子式 C9H13N3O5
分子量243.22
储存条件2-8 °C 冷藏保存。
性质
Appearance (Color) White
Appearance (Form) Powder
Solubility (Color) Colorless
Solubility (Turbidity) Clear
  50 mg/ml, H2O
EmM 13.0 - 13.6
  in 0.1 M HCl
Wavelength 279 - 282 nm
Purity (HPLC) ≥90 %
原产地美国
描述

Biochem/physiol Actions

阿糖胞苷复合到 DNA 中后,可通过与导致 DNA 断裂的拓扑异构酶 I 形成可裂解复合物而抑制 DNA 的复制,但不会抑制 RNA 的合成。抗白血病制剂。

供货状态True
参考文献

Ciofani, G., et al., In Vitro And In Vivo Biocompatibility Testing Of Functionalized Carbon Nanotubes. Methods Mol. Biol. 625, 67-83, (2010)

Musarò, A., and Barberi, L., Isolation And Culture Of Mouse Satellite Cells. Methods Mol. Biol. 633, 101-11, (2010)

Götte, M., et al., An Imaging Assay To Analyze Primary Neurons For Cellular Neurotoxicity. J. Neurosci. Methods 192, 16-Jul, (2010)

Willis, D.E., and Twiss, J.L., Profiling Axonal MRNA Transport. Methods Mol. Biol. 714, 335-52, (2011)

Di Stefano, V., et al., Knockdown Of Cyclin-dependent Kinase Inhibitors Induces Cardiomyocyte Re-entry In The Cell Cycle. J. Thorac. Cardiovasc. Surg. 286, 8644-54, (2011)

Babiarz, J., et al., Juvenile And Adult Olfactory Ensheathing Cells Bundle And Myelinate Dorsal Root Ganglion Axons In Culture. Experimental Neurology 229, 72-9, (2011)

Merck 14,2784

Beil. 25,IV,3669

类型核酸 & 衍生物
安全信息
符号 GHS07GHS08
信号词 Warning
危险声明 H317-H361
警示性声明 P280
个人防护装备 Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
危害码 Xn
风险声明 43-63
安全声明 36/37
WGK德国 3
RTECS HA5425000