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中文名称英文名称CAS 编号规格目录价所属品牌订货号
青霉素 G 钠盐Penicillin G sodium salt69-57-81G¥150.00SIGMAPENNA
青霉素 G 钠盐Penicillin G sodium salt69-57-85G¥462.00SIGMAPENNA
青霉素 G 钠盐Penicillin G sodium salt69-57-825G¥1,309.00SIGMAPENNA
品牌SIGMA
产品名称 青霉素 G 钠盐 : Penicillin G sodium salt ——【产品编号:SIGMA-PENNA】
CAS编号69-57-8
别名青霉素G钠盐,青霉素钠盐,苄基青霉素钠盐,苄青霉素钠盐,Benzylpenicillin sodium salt
级别科学级
纯度&分析~1650 U/mg
Tips一种常用的研究级抗生素类制品,可抑制细菌细胞壁合成。
分子式 C16H17N2NaO4S
分子量356.37
储存条件常温避光保存。
性质
Appearance (Color) White to Off-White
Appearance (Form) Powder
Solubility (Color) Colorless to Faint Yellow
Solubility (Turbidity) Clear
  100 mg/mL, H2O
Infrared spectrum Conforms to Structure
Moisture Content ≤1.5 %
Potency 1645 - 1675
  units Penicillin-G base/mg of solid
原产地美国
描述

Biochem/physiol Actions

Mode of Action: Inhibits bacterial cell wall synthesis.
Antimicrobial spectrum: Gram-positive bacteria.

Penicillin G is active against gram-positive and gram-negative aerobic and anaerobic bacteria. Penicillin G inhibits cell wall synthesis by binding to penicillin binding proteins (PBPs), which inhibits peptidoglycan chain cross-linking. Penicillin G is stable against hydrolysis by β-lactamases, such as penicillinases and cephalosporinases.

Application

Penicillin G is narrow spectrum antibiotic. It is the drug of choice for Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. Penicillin G sodium salt is used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility 1. It is used in cell culture alone as well as in combination with streptomcyin and other antibiotics2.

供货状态True
参考文献

1. P Giesbrecht, T Kersten, et al., Fan-shaped ejections of regularly arranged murosomes involved in penicillin-induced death of Staphylococci. J. Bacteriol. 174, 2241-2252, (1992)

2. P Salanitro, P A Muirhead, et al., Morphological and physiological characteristics of Gemmiger formicilis isolated from chicken ceca. Appl. Environ. Microbiol. 32, 623-632, (1976)

Martin, H.H. and Gmeiner, J., Modification of peptidoglycan structure by penicillin action in cell walls of Proteus mirabilis. Eur. J. Biochem. 95, 487, (1979)

Merck 14,7094

Beil. 27,IV,5861

类型抗生素
安全信息
符号  GHS08
信号词  Danger
危险声明  H317-H334
警示性声明  P261-P280-P342 + P311
个人防护装备  dust mask type N95 (US), Eyeshields, Faceshields, Gloves
危害码  Xn
风险声明  42/43
安全声明  22-36/37-45
WGK德国  2
RTECS  XH9800000