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中文名称英文名称CAS 编号规格目录价所属品牌订货号
正钒酸钠Sodium orthovanadate13721-39-610G¥270.00SIGMAS6508
正钒酸钠Sodium orthovanadate13721-39-650G¥930.00SIGMAS6508
正钒酸钠Sodium orthovanadate13721-39-6250G¥4,100.00SIGMAS6508
品牌SIGMA
产品名称 正钒酸钠 : Sodium orthovanadate ——【产品编号:SIGMA-S6508】
CAS编号13721-39-6
别名原钒酸钠
级别科学级
纯度&分析≥90% (titration)
TipsBSZH品质推荐:SIGMA-ALDRICH 进口高等级试剂,多重遴选,国际标准严苛测试,全球生物化学产品质量标杆,满足用户更高应用要求。 使用SIGMA-ALDRICH品质优异、表现卓越的试剂类产品,将有助于使您的研究项目更早获益。
分子式Na3VO4
分子量183.91
储存条件常温避光保存。
性质

~InChI Key   IHIXIJGXTJIKRB-UHFFFAOYSA-N
assay   ≥90% (titration)
color   white to off-white
mp   850-866 °C(lit.)
solubility   H2O: soluble

原产地美国
描述

~Biochem/physiol Actions
抑制 ATP 酶、碱性磷酸酶和酪氨酸磷酸酶。在酸性 PH 值下形成的十钒酸盐可抑制肌醇基 1,4,5-三磷酸 (IP3)-诱导 Ca2+ 从内分泌细胞中的释放以及阻止 IP3 与其受体在脑组织中的结合。
Sodium orthovandate suppresses the activation of p53-mediated apoptosis triggered in response to radiation. It reduces the detrimental effects of hematopoietic syndrome, hematopoiesis and delayed genotoxic effects of induced by total body irradiation of mice.24 In combination with menadione, orthovandate prevents the migration of detached human glioma cells in response to anti-cancer drugs.25

Application
Sodium orthovandate was used to prepare the stop solution in dephosphorylation assay of insulin receptor kinase.26 It was one of the reagents used in the development of Matrix ChIP that utilizes surface-immobilized antibodies.27
Features and Benefits
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

供货状态True
参考文献N/A
类型BSZH 高等级基础试剂
安全信息

~符号  GHS07  GHS07
信号词  Warning
危害声明  H302
警示性声明  P301 + P312 + P330
个人防护装备  dust mask type N95 (US), Eyeshields, Faceshields, Gloves
危害码 (欧洲)  Xn
风险声明 (欧洲)  20/21/22
安全声明 (欧洲)  22-36
RIDADR  NONH for all modes of transport
WGK德国  3
RTECS  YW1120000