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中文名称英文名称CAS 编号规格目录价所属品牌订货号
腺苷Adenosine58-61-75G248.00SIGMAA9251
腺苷Adenosine58-61-725G892.00SIGMAA9251
腺苷Adenosine58-61-7100G2,325.00SIGMAA9251
腺苷Adenosine58-61-71KG17,206.00SIGMAA9251
腺苷Adenosine58-61-75KG58,500.00SIGMAA9251
品牌SIGMA
产品名称 腺苷 : Adenosine ——【产品编号:SIGMA-A9251】
CAS编号58-61-7
别名9-β-D-呋喃核糖基腺嘌呤,腺嘌呤-9-β-D-呋喃核糖苷,腺嘌呤核苷,阿糖腺苷
级别科学级
纯度&分析≥99%
Tips腺苷受体处的内源性神经递质。
分子式 C10H13N5O4
分子量267.24
储存条件2-8 °C 冷藏保存。
性质
Appearance (Color) White
Appearance (Form) Powder
Solubility (Color) Colorless
Solubility (Turbidity) Clear
  200 mg + 4 mL, 1 M NH4OH
UV/Vis absorbance 14.6 - 15.2
  pH 7.0
Wavelength 259 - 260 nm
Purity (HPLC) ≥99 %
原产地美国
描述

Biochem/physiol Actions

腺苷受体处的内源性神经递质。心肌保护作用可能与 A1 腺苷受体的激活有关。通过 A2 腺苷受体可介导腺苷的抗血小板和抗炎作用。相比之下,腺苷在哮喘和慢性阻塞性肺部疾病 (COPD) 中起促炎介质作用。

供货状态True
参考文献

Liu, X., et al., Induction Of Cell Cycle Arrest At G1 And S Phases And CAMP-dependent Differentiation In C6 Glioma By Low Concentration Of Cycloheximide. BMC Cancer 10, 684, (2010)

Díez-Zaera, M., et al., Tissue-nonspecific Alkaline Phosphatase Promotes Axonal Growth Of Hippocampal Neurons. Molecular Biology of the Cell 22, 1014-24, (2011)

Hutchinson, S.A., and Scammells, P.J., A1 adenosine receptor agonists: medicinal chemistry and therapeutic potential. Curr. Pharm. Des. 10, 2021-2039, (2004)

Fredholm, B.B., et al., Actions of Adenosine at Its Receptors in the CNS: Insights from Knockouts and Drugs. Annu. Rev. Pharmacol. 27, (2004)

Livingston, M., et al., Adenosine, inflammation and asthma--a review. Inflamm. Res. 53, 171-178, (2004)

Sullivan, G.W., Adenosine A2A receptor agonists as anti-inflammatory agents. Curr. Opin. Investig. Drugs 4, 1313-1319, (2003)

Rorke, S., and Holgate, S.T., Targeting adenosine receptors: novel therapeutic targets in asthma and chronic obstructive pulmonary disease. Am. J. Respir. Med. 1, 99-105, (2002)

Merck 14,153

Beil. 26,IV,3598

FT-IR 1 (2), 720:A / FT-IR 2 (3), 3684:C / FT-NMR 1 (3), 222:A / IR-Spectra (3), 1296:E / IR-Spectra (2), 1128:F / NMR-Reference 2 (2), 597:C / RegBook 1 (2), 2475:K / Sax 6, 138 / Sigma FT-IR 1 (1), 752:C / Structure Index 1, 391:A:6

类型核酸 & 衍生物
安全信息
个人防护装备 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK德国 2