中文名称英文名称CAS 编号规格所属品牌订货号
5'-二磷酸尿苷二钠盐(UDP)Uridine 5′-diphosphate disodium salt hydrate27821-45-0100MGSIGMA94330
5'-二磷酸尿苷二钠盐(UDP)Uridine 5′-diphosphate disodium salt hydrate27821-45-0500MGSIGMA94330
5'-二磷酸尿苷二钠盐(UDP)Uridine 5′-diphosphate disodium salt hydrate27821-45-05GSIGMA94330
品牌SIGMA
产品名称 5'-二磷酸尿苷二钠盐(UDP) : Uridine 5′-diphosphate disodium salt hydrate ——【产品编号:SIGMA-94330】
CAS编号27821-45-0
别名5′-UDP-Na2,UDP Na2,UDP钠盐,UDP二钠盐,尿苷-5'-二磷酸二钠盐
级别科学级
纯度&分析≥96.0% (HPLC)
Tips一种常见的核酸类衍生物。
分子式 C9H12N2Na2O12P2 · xH2O
分子量448.12 (anhydrous basis)
储存条件-20 °C 低温冷冻保存。
性质
assay ≥96.0% (HPLC)
total impurities ≤15% water
storage temp. −20°C
原产地美国
描述

Application

Uridine 5′-diphosphate (UDP) and Uridine 5′-triphosphate (UTP) may be used in studies on nucleic acid (RNA) biosynthesis and cell signaling. UDP is a nucleotide that upon phosphorylation to UTP becomes a substrate for enzymes such as RNA polymerase(s) and GTPases. These enzymes are involved in a wide range of applications from the synthesis of RNA to the regulation of G-coupled Protein Receptors (GPCR) and cell signaling molecules such as Rho-signaling via Guanine Nucleotide Exchange Factors (GEF).

供货状态True
参考文献

Yoshimura S, Gerondopoulos A, et al., Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors. J. Cell Biol. 191, 367-381, (2010)

Wright SJ, Inchausti R, Eaton CJ, et al., RIC8 Is a Guanine-Nucleotide Exchange Factor for G{alpha} Subunits That Regulates Growth and Development in Neurospora crassa. Genetics 189, 165-176, (2011)

Liot C, Seguin L, Siret A, Crouin C, et al., APC Mediates Degradation of the Oncogenic Rho-GEF Ect2 after Mitosis. PLoS ONE 6, e23676, (2011)

Ding F, Yin Z, Wang HR., Ubiquitination in Rho signaling. Curr. Top. Med. Chem 11(23), 2879-2887, (2011)

Beil. 24,IV,1214

类型核酸 & 衍生物
安全信息
符号 GHS07
信号词 Warning
危险声明 H315-H319-H335
警示性声明 P261-P305 + P351 + P338
个人防护装备 dust mask type N95 (US), Eyeshields, Gloves
危害码 Xi
风险声明 36/37/38
安全声明 26-36
WGK德国 3