Caution

如果需要无菌溶液，则应采用无菌过滤而非高压灭菌。时间一长，亚精胺将发生脱氨基作用；溶液应采用冷冻保存。通常需要配制新溶液。

包装

1, 5, 25 g in glass btl

Biochem/physiol Actions

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T₄ polynucleotide kinase activity.

Warf, M.B., et al., Pentamidine reverses the splicing defects associated with myotonic dystrophy. PLoS Pathog. 106, 18551-18556, (2009)

Krug, M.S., Berger, S.L. Meth. Enzymol. 152, 321, (1987)

Hu, J., et al., Polyamines inhibit nitric oxide synthase in rat cerebellum. Neurosci. Lett. 175, 41-45, (1994)

Cull, M., and McHenry, C.S., Preparation of extracts from prokaryotes. Meth. Enzymol. 182, 147-153, (1990)

Baumann P, et al., Purification of human Rad51 protein by selective spermidine precipitation. Mutat. Res. 384, 65-72, (1997)

Tabor, C.W., Tabor, H. Annu. Rev. Biochem. 53, 749, (1984)

Bouché, J.P. Anal. Biochem. 115, 42, (1981)

Blethen, S.L. J. Biol. Chem. 243, 1671, (1968)

Wu, W.H., Morris, D.R. J. Biol. Chem. 248, 1687, (1973)

Karkas, J.D. J. Biol. Chem. 250, 8657, (1975)

Merck 14,8742

Beil. 4,IV,1300

Aldrich MSDS 1, 1616:D / Corp MSDS 1 (2), 3164:C / FT-IR 2 (1), 486:C / FT-IR 1 (1), 309:D / FT-NMR 1 (1), 501:B / IR-Spectra (3), 180:F / IR-Spectra (2), 163:C / NMR-Reference 2 (1), 266:D / RegBook 1 (1), 331:G / Sax 6, 2460 / Sigma FT-IR 1 (2), 23:C / Structure Index 1, 45:C:9