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中文名称英文名称CAS 编号规格目录价所属品牌订货号
还原型辅酶 II(NADPH,四钠盐)β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrateN/A25MG¥585.00SIGMAN7505
还原型辅酶 II(NADPH,四钠盐)β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrateN/A100MG¥1,760.00SIGMAN7505
还原型辅酶 II(NADPH,四钠盐)β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrateN/A500MG¥7,420.00SIGMAN7505
还原型辅酶 II(NADPH,四钠盐)β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrateN/A1G¥11,900.00SIGMAN7505
品牌SIGMA
产品名称 还原型辅酶 II(NADPH,四钠盐) : β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrate ——【产品编号:SIGMA-N7505】
CAS编号N/A
别名还原型辅酶 II 四钠盐,β-NADPH,2′-NADPH 水合物,NADPH Na4,TPNH2 Na4,二氢烟酰胺腺嘌呤二核苷酸磷酸四钠盐,还原型三磷酸吡啶核苷酸四钠盐
级别科学级
纯度&分析≥97% (HPLC)
Tips还原型 β-烟酰胺腺嘌呤二核苷酸 2′-磷酸四钠盐水合物。
分子式 C21H26N7Na4O17P3 · xH2O
分子量833.35 (anhydrous basis)
储存条件-20 °C 低温冷冻保存。
性质
Quality Level PREMIUM
assay ≥97% (HPLC)
  ≥97% (spectrophotometric assay)
storage temp. −20°C
原产地美国
描述

Biochem/physiol Actions

电子供体;很多氧化还原酶(包括一氧化氮合成酶)的辅因子

Other Notes

根据固体质量包装。

Preparation Note

Chemically reduced

Application

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

供货状态True
参考文献

Canevari L, Clark JB., Alzheimer's disease and cholesterol: the fat connection. Neurochem. Res. 32, 739-750, (2007)

Fraser PA., The role of free radical generation in increasing cerebrovascular permeability. Free Radic. Biol. Med. 51, 967-977, (2011)

Drummond GR, Selemidis S, et al., Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets. Nat. Rev. Drug Discov. 10, 453-471, (2011)

Brann D, Raz L, Wang R, et al., Estrogen signaling and neuroprotection in cerebral ischemia. J. Neuroendocrinol. 24(1), 34-47, (2011)

Beil. 26,IV,3672

类型酶 & 辅酶
安全信息
个人防护装备 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
风险声明 36/37/38
安全声明 26
WGK德国 1