中文名称英文名称CAS 编号规格所属品牌订货号
特美汀(替卡西林)Ticarcillin disodium salt(Timentin)4697-14-73.2GSIGMAT5639
特美汀(替卡西林)Ticarcillin disodium salt(Timentin)4697-14-710X3.2GSIGMAT5639
品牌SIGMA
产品名称 特美汀(替卡西林) : Ticarcillin disodium salt(Timentin) ——【产品编号:SIGMA-T5639】
CAS编号4697-14-7
别名替卡西林二钠盐,特美汀二钠盐,Timentin
级别科学级
纯度&分析≥95%
Tips一种新型革兰氏阴性菌抗生素。
分子式

C15H14N2Na2O6S2

分子量428.39
储存条件2-8 °C 冷藏保存。
性质
Related Categories Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics T-Z, Antibiotics by Application,
Biochemicals and Reagents, Chemical Structure Class, Genetic Marker Selection, Interferes with Cell Wall Synthesis, L - Z, Mechanism of Action, Penicillins and Cephalosporins (beta-Lactams), Spectrum of Activity
assay   ≥95%
storage temp.   2-8°C
原产地美国
描述
Other Notes

β-Lactam antibiotic

Application

Ticarcillin is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria. It is commonly used in combination with clavulanate in order to improve it′s efficacy1. It is used to study appropriate dosing in pediatric patients who have cystic fibrosis2.

Biochem/physiol Actions

Ticarcillin is a β-Lactam antibiotic that prevents bacterial cell wall biosynthesis at the level of peptidogylcan cross-linking by inhibiting peptidoglycan transpeptidases. It is derived from penicillin and is similar to carbenicillin in action. Ticarcillin is susceptible to degradation by ß-lactamases1

供货状态True
参考文献

1、C Knox et. al
Nucleic Acids Research, 39(Database), D1035-D1041 (2011)

2、Jeffery T Zobell et. al
Journal of Cystic Fibrosis, 9(4), 280-283 (2010)

3、R N Brogden et. al
Drugs, 20(5), 325-352 (1980)

4. Merck 14,9428

类型抗生素
安全信息
符号  GHS07GHS08  
信号词  Danger
危险声明  H315-H319-H334-H335
警示性声明  P261-P305 + P351 + P338-P342 + P311
个人防护装备  dust mask type N95 (US), Eyeshields, Faceshields, Gloves
危害码 (欧洲)  Xn
风险声明 (欧洲)  36/37/38-42-43
安全声明 (欧洲)  26-36/37
WGK德国  2
RTECS  XM9410000