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中文名称英文名称CAS 编号规格目录价所属品牌订货号
匹鲁卡品盐酸盐Pilocarpine hydrochloride54-71-7100MG¥1,412.45SIGMAP6503
匹鲁卡品盐酸盐Pilocarpine hydrochloride54-71-71G¥4,586.22SIGMAP6503
匹鲁卡品盐酸盐Pilocarpine hydrochloride54-71-75G¥15,200.18SIGMAP6503
匹鲁卡品盐酸盐Pilocarpine hydrochloride54-71-710G¥27,620.57SIGMAP6503
匹鲁卡品盐酸盐Pilocarpine hydrochloride54-71-725G¥56,970.43SIGMAP6503
品牌SIGMA
产品名称 匹鲁卡品盐酸盐 : Pilocarpine hydrochloride ——【产品编号:SIGMA-P6503】
CAS编号54-71-7
别名盐酸匹鲁卡品,毛果芸香碱盐酸盐,(3S,4R)-4,5-二氢-3-乙基-4-(1-甲基-1H-咪唑-5-基甲基)-2(3H)-呋喃酮盐酸盐
级别科学级
纯度&分析≥98% (titration), powder.
Tips非选择性毒蕈碱型乙酰胆碱受体激动剂,用于建立癫痫的实验模型。
分子式 C11H16N2O2 · HCl
分子量244.72
储存条件常温避光保存。
性质
assay ≥98% (titration)
form powder
color white
mp 202-205 °C(lit.)
solubility H2O: soluble100 mg/mL
原产地美国
描述

Biochem/physiol Actions

非选择性毒蕈碱型乙酰胆碱受体激动剂;用于建立癫痫的实验模型。

Caution

Hygroscopic, light sensitive.

Other Notes

Shelf life of the powder is at least five years.

供货状态True
参考文献

Liu, Y.H., et al., Up-regulation Of D-serine Might Induce GABAergic Neuronal Degeneration In The Cerebral Cortex And Hippocampus In The Mouse Pilocarpine Model Of Epilepsy. Neurochem. Res. 34, 1209-18, (2009)

Goffin, K., et al., Longitudinal MicroPET Imaging Of Brain Glucose Metabolism In Rat Lithium-pilocarpine Model Of Epilepsy. Experimental Neurology 217, 205-9, (2009)

Ndode-Ekane, X.E., et al., Vascular Changes In Epilepsy: Functional Consequences And Association With Network Plasticity In Pilocarpine-induced Experimental Epilepsy. Neuroscience 166, 312-32, (2010)

Dube, C., et al., Progressive metabolic changes underlying the chronic reorganization of brain circuits during the silent phase of the lithium-pilocarpine model of epilepsy in the immature and adult rat. Exp. Neurol. 162, 146-157, (2000)

Mayorga, A.J., et al., Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. Eur. J. Pharmacol. 364, 7-11, (1999)

Cavalheiro, E.A., The pilocarpine model of epilepsy. Ital. J. Neurol. Sci. 16, 33-37, (1995)

Maslanski, J.A., et al., Assessment of the muscarinic receptor subtypes involved in pilocarpine-induced seizures in mice. Neurosci. Lett. 168, 225-228, (1994)

Merck 14,7424

Beil. 27,II,695

Aldrich MSDS 1, 1495:B / Corp MSDS 1 (2), 2838:A / FT-IR 2 (3), 3524:A / FT-IR 1 (2), 624:C / FT-NMR 1 (3), 86:C / IR-Spectra (3), 1224:C / IR-Spectra (2), 1065:E / NMR-Reference 2 (2), 496:B / RegBook 1 (2), 2365:B / Sax 6, 2232 / Sigma FT-IR 1 (1), 598:A / Structure Index 1, 375:D:1

类型BSZH 生物化学研究
安全信息
符号 GHS06
信号词 Danger
危险声明 H300-H330
警示性声明 P260-P264-P284-P301 + P310-P310
危害码 T+
风险声明 26/28
安全声明 25-45
RIDADR UN 1544 6.1/PG 3
WGK德国 3