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中文名称英文名称CAS 编号规格目录价所属品牌订货号
呋喃唑酮Furazolidone67-45-825G¥1,100.00SIGMAF9505
呋喃唑酮Furazolidone67-45-8100G¥3,020.00SIGMAF9505
品牌SIGMA
产品名称 呋喃唑酮 : Furazolidone ——【产品编号:SIGMA-F9505】
CAS编号67-45-8
别名3-(5-硝基呋喃甲叉氨基)-2-噁唑烷酮
级别科学级
纯度&分析powder
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分子式C8H7N3O5
分子量225.16
储存条件常温避光保存。
性质

用途:生化研究。具有较广抗菌谱的杀菌剂。

性状:黄色结晶性粉末。极为溶于氯仿、水、乙醇和四氯化碳,11水中溶40mg该品。稍溶于二甲基甲酰胺。无臭、味苦。

biological source   Organic from synthetic
InChI Key   PLHJDBGFXBMTGZ-WEVVVXLNSA-N
form   powder
color   yellow
mp   256-256 °C
solubility   formic acid: soluble50 mg/mL
Mode of action   enzyme | inhibits
antibiotic activity spectrum   Gram-positive bacteria
  parasites

原产地美国
描述

Application
Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA, which leads to the gradual inhibition of monoamine oxidase. It is used to treat anorexia and antagonism of thiamin utilization in poultry[1]. Furazolidone increases thapsigargin-sensitive Ca2+-ATPase in chick cardiac myocytes[2].


Biochem/physiol Actions
Furazolidone and its generated free radicals, may bind to DNA and induce cross-links. Bacterial DNA is particularly susceptible to this drug, which results in high levels of mutations (transitions and transversions) in the bacterial chromosome. Its mechanism of action minimizes the development of resistant organisms. Furazolidone is a monoamine oxidase (MAO) inhibitor and is used as a DNA interstrand cross-linking agent.

供货状态True
参考文献N/A
类型抗生素
安全信息

符号  GHS08  GHS08
信号词  Warning
危害声明  H361
警示性声明  P281
个人防护装备  Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
危害码 (欧洲)  Xn
风险声明 (欧洲)  62
安全声明 (欧洲)  36
RIDADR  NONH for all modes of transport
WGK德国  3
RTECS  RQ3675000