中文名称英文名称CAS 编号规格所属品牌订货号
5′-二磷酸腺苷二钠盐(ADP)Adenosine 5′-diphosphate disodium salt16178-48-6250MGFLUKA01897
5′-二磷酸腺苷二钠盐(ADP)Adenosine 5′-diphosphate disodium salt16178-48-61GFLUKA01897
5′-二磷酸腺苷二钠盐(ADP)Adenosine 5′-diphosphate disodium salt16178-48-65GFLUKA01897
品牌FLUKA
产品名称 5′-二磷酸腺苷二钠盐(ADP) : Adenosine 5′-diphosphate disodium salt ——【产品编号:FLUKA-01897】
CAS编号16178-48-6
别名5′-ADP-Na2,5′-ADP Na2,腺苷-5′-二磷酸二钠盐,焦磷酸腺苷,ADP钠盐
级别科学级
纯度&分析≥90%
Tips一种常见的核酸类衍生物。
分子式 C10H13N5Na2O10P2
分子量471.16
储存条件-20 °C 低温冷冻保存。
性质
assay ≥90%
optical activity [α]20/D −29.6±1°, c = 0.5% in 0.5 M Na2HPO4
total impurities ≤10% water
storage temp. −20°C
原产地美国
描述

Application

Adenosine 5′-diphosphate (ADP) is an adenine nucleotide involved in energy storage and nucleic acid metabolism via its conversion into ATP by ATP synthases. ADP affects platelet activation through its interaction with ADP receptors P2Y1, P2Y12 and P2X1. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.

供货状态True
参考文献

Erlinge D., P2Y receptors in health and disease. Adv. Pharmacol. 61, 417-439, (2011)

Iyú D, Glenn JR, White AE, Fox SC, Heptinstall S., Adenosine derived from ADP can contribute to inhibition of platelet aggregation in the presence of a P2Y12 antagonist. Arterioscler. Thromb. Vasc. Biol., 416-422, (2011)

Jones S, Evans RJ, Mahaut-Smith MP., Extracellular Ca(2+) modulates ADP-evoked aggregation through altered agonist degradation: implications for conditions used to study P2Y receptor activation. Br. J. Haematol. 153, 83-91, (2011)

Hechler B, Gachet C., P2 receptors and platelet function. Purinergic Signal. 7(3), 293-303, (2011)

Beil. 26,IV,3629

类型核酸 & 衍生物
安全信息
个人防护装备 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
安全声明 22-24/25
WGK德国 3