| 品牌 |  |
| 产品名称 |
可溶性两性霉素 B ： Amphotericin B solubilized ——【产品编号：SIGMA-A9528】
|
| CAS编号 | 1397-89-3 |
| 别名 | 二性霉素B，节丝霉素B，两性霉素-B，两性霉素乙，芦山霉素，庐山霉素，异性霉素，Amphotericin B from Streptomyces sp., Fungizone， |
| 级别 | 生化级 |
| 纯度&分析 | powder, γ-irradiated, BioXtra, suitable for cell culture |
| Tips | 两性霉素B为多烯类抗真菌抗生素，通过影响细胞膜通透性发挥抑制真菌生长的作用。 |
| 分子式 |
C47H73NO17
|
| 分子量 | 924.08 |
| 储存条件 | 2-8 °C 冷藏保存。 |
| 性质 |
|
sterility |
γ-irradiated |
|
product line |
BioXtra |
|
form |
powder |
|
solubility |
sterile water: soluble20 mg/mL (as a stock solution. Stock solutions should be stored at −20 °C. Stable at 37 °C for 3 days.) |
|
suitability |
suitable for cell culture |
|
storage temp. |
2-8°C |
|
| 原产地 | 美国 |
| 描述 |
Application
Recommended for use in cell culture applications at 5.6 mg (solid)/L. It is used to study the formation of ion-permeable channels in fungal cell membranes
Biochem/physiol Actions
Mode of Action: Interferes with fungal membrane permeability by forming channels in the membranes and causing small molecules to leak out.
Polyene antifungal antibiotic from Streptomyces. Affinity for sterols, primarily ergosterols, of fungal cell membranes. Forms channels in the membranes, causing small molecules to leak out.
Antimicrobial spectrum: fungi and yeast.
|
| 供货状态 | True |
| 参考文献 |
Perlman, D., Use of antibiotics in cell culture media. Meth. Enzymol. LVIII, 112, (1979)
Merck 14,585
Beil. 18,V,10,525
|
| 类型 | 抗生素 |
| 安全信息 |
|
符号 |
 |
|
信号词 |
Warning |
|
危险声明 |
H315-H319-H335 |
|
警示性声明 |
P261-P305 + P351 + P338 |
|
个人防护装备 |
dust mask type N95 (US), Eyeshields, Gloves |
|
危害码 |
Xn |
|
风险声明 |
22-36/37/38 |
|
安全声明 |
26 |
|
WGK德国 |
3 |
|