中文名称英文名称CAS 编号规格所属品牌订货号
万古霉素盐酸盐Vancomycin hydrochloride from Streptomyces orientalis1404-93-9100MGSIGMAV2002
万古霉素盐酸盐Vancomycin hydrochloride from Streptomyces orientalis1404-93-9250MGSIGMAV2002
万古霉素盐酸盐Vancomycin hydrochloride from Streptomyces orientalis1404-93-91GSIGMAV2002
万古霉素盐酸盐Vancomycin hydrochloride from Streptomyces orientalis1404-93-95GSIGMAV2002
品牌SIGMA
产品名称 万古霉素盐酸盐 : Vancomycin hydrochloride from Streptomyces orientalis ——【产品编号:SIGMA-V2002】
CAS编号1404-93-9
别名盐酸万古霉素,Vancomycin HCL
级别科学级
纯度&分析potency: ≥900 μg per mg (as vancomycin base)
Tips为窄谱抗生素,仅对革兰阳性菌有效,如溶血性链球菌、肺炎球菌、淋球菌及肠球菌等均属敏感,对耐药金葡菌本品尤为敏感。
分子式 C66H75Cl2N9O24 · HCl
分子量1485.71
储存条件2-8 °C 冷藏保存。
性质
Appearance (Color) White to Orange-Brown
Appearance (Form) Powder
Solubility (Color) Faint Yellow to Faint Orange
Solubility (Turbidity) Clear
  50 mg/ml, H2O
% Water ≤10
  by Karl Fischer
Carbon (anhydrous) 50.7 - 56.0 %
Nitrogen (anhydrous) 8.0 - 8.9 %
ug Vancomycin/mg ≥900
  Anhydrous Basis (assay/potency)
原产地美国
描述

Biochem/physiol Actions

Glycopeptide antibiotic
Mode of action: Used to block bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis by inhibiting incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides.
Antimicrobial spectrum: Gram-positive bacteria

Other Notes

Studies on bond strength in vancomycin-peptide complexes.1 Structure of vancomycin and its complex with acetyl-D-alanyl-D-alanine.2

供货状态True
参考文献

1. Williamson, M.P., and Williams, D.H. Eur. J. Biochem. 138, 345, (1984)

2. Sheldrick, et al. Nature 271, 223, (1978)

Merck 14,9929

Beil. 27,IV,9719

类型抗生素
安全信息
符号  GHS07
信号词  Warning
危险声明  H317
警示性声明  P280
个人防护装备  dust mask type N95 (US), Eyeshields, Faceshields, Gloves
危害码  Xi
风险声明  43
安全声明  36/37
WGK德国  2
RTECS  YW4380000