品牌 |  |
产品名称 |
核糖核酸酶抑制剂 : Ribonuclease Inhibitor ——【产品编号:SIGMA-R2520】
|
CAS编号 | N/A |
别名 | Ribonuclease inhibitor human,RNA酶抑制剂,RNasin Inhibitor |
级别 | 科学级 |
纯度&分析 | ~30-50 units/μL |
Tips | 来源于人胎盘。 |
分子式 | N/A |
分子量 | N/A |
储存条件 | -20 °C 低温冷冻保存。 |
性质 |
mol wt |
mol wt ~50 kDa |
concentration |
30,000-50,000 units/mL |
shipped in |
dry ice |
storage temp. |
−20°C |
|
原产地 | 美国 |
描述 |
Application
Useful for in vitro inhibition of ribonucleases, including procedures like cDNA synthesis, RT-PCR, and in vitro transcription and translation.
Other Notes
This inhibitor of RNase activity is isolated from human placenta and supplied as a buffered aqueous glycerol solution.
Unit Definition
One unit will reduce the activity of 5 ng of ribonuclease A by 50% in a cytidine 2′:3′-cyclic monophosphate system.
Physical form
Solution in 50% glycerol, 20 mM HEPES-KOH, pH 7.6, 50 mM KCl and 8 mM DTT
Biochem/physiol Actions
Inhibits RNase by forming a tight, non-covalent 1:1 complex. Also inhibits angiogenin, a neovascularization promoter which is homologous with RNase A.1
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供货状态 | True |
参考文献 |
Blackburn, P., Ribonuclease inhibitor from human placenta: interaction with derivatives of ribonuclease A. J. Biol. Chem. 254, 12488-12493, (1979) 摘要
Blackburn, P. J. Biol. Chem. 254, 12484, (1979)
|
类型 | 酶 & 辅酶 |
安全信息 |
符号 |
 |
信号词 |
Warning |
危险声明 |
H315-H319 |
警示性声明 |
P305 + P351 + P338 |
个人防护装备 |
Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
危害码 |
B |
安全声明 |
24/25 |
WGK德国 |
3 |
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