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中文名称英文名称CAS 编号规格目录价所属品牌订货号
硫酸鱼精蛋白Protamine sulfate salt from salmon53597-25-41G¥180.00SIGMAP4020
硫酸鱼精蛋白Protamine sulfate salt from salmon53597-25-45G¥450.00SIGMAP4020
硫酸鱼精蛋白Protamine sulfate salt from salmon53597-25-425G¥3,020.00SIGMAP4020
硫酸鱼精蛋白Protamine sulfate salt from salmon53597-25-4100G¥10,506.00SIGMAP4020
品牌SIGMA
产品名称 硫酸鱼精蛋白 : Protamine sulfate salt from salmon ——【产品编号:SIGMA-P4020】
CAS编号53597-25-4
别名鱼精蛋白硫酸盐,鲑精蛋白,鲑精朊,salmine,salmosalar protamine,protamine,nucleoprotamine,protamines
级别科学级
纯度&分析Grade X, amorphous powder
Tips来源于鲑鱼。
分子式N/A
分子量N/A
储存条件常温避光保存。
性质
type Grade X
form amorphous powder
total impurities histone, free (Millon test)
color white
solubility H2O: soluble10 mg/mL
原产地美国
描述

Application

Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.

可用于从蛋白样品中除去 DNA 或用于 DNA 结合蛋白的纯化。在逆转录病毒介导的基因转移中可用作聚凝胺的替代物。

Biochem/physiol Actions

硫酸鱼精蛋白是一种可与 DNA 结合并产生沉淀的小阳离子蛋白。它能中和肝素的抗凝血活性,还可抑制脂蛋白脂肪酶。

供货状态True
参考文献

Choi, S., et al., The design and evaluation of heparin-binding foldamers. Angew. Chem. Int. Ed. Engl. 44, 6685-9, (2005)

Bailey, S.N., et al., Microarrays of lentiviruses for gene function screens in immortalized and primary cells. Nature Methods 3, 117-22, (2006)

Hauser, P.V., et al., Novel siRNA delivery system to target podocytes in vivo. PLoS ONE 5, 9463, (2010)

Sanders, M. Anal. Biochem. 103, 157-165, (1980)

Vighi, E., et al., Nuclear localization of cationic solid lipid nanoparticles containing protamine as transfection promoter Eur. J. Pharm. Biopharm. 76, 384-393, (2010)

Merck 14,8338

类型蛋白质
安全信息
个人防护装备 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK德国 3