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中文名称英文名称CAS 编号规格目录价所属品牌订货号
还原型辅酶 I(NADH,二钾盐)β-Nicotinamide adenine dinucleotide, reduced dipotassium salt104809-32-7100MG¥690.00SIGMAN4505
还原型辅酶 I(NADH,二钾盐)β-Nicotinamide adenine dinucleotide, reduced dipotassium salt104809-32-7500MG¥2,235.00SIGMAN4505
还原型辅酶 I(NADH,二钾盐)β-Nicotinamide adenine dinucleotide, reduced dipotassium salt104809-32-71G¥4,170.00SIGMAN4505
还原型辅酶 I(NADH,二钾盐)β-Nicotinamide adenine dinucleotide, reduced dipotassium salt104809-32-75G¥16,260.00SIGMAN4505
品牌SIGMA
产品名称 还原型辅酶 I(NADH,二钾盐) : β-Nicotinamide adenine dinucleotide, reduced dipotassium salt ——【产品编号:SIGMA-N4505】
CAS编号104809-32-7
别名还原型辅酶 I 二钾盐,β-DPNH,β-NADH,DPNH,Diphosphopyridine nucleotide,reduced form NADH
级别科学级
纯度&分析≥95%
Tips还原型 β-烟酰胺腺嘌呤二核苷酸二钾盐,无水。
分子式 C21H27N7O14P2K2
分子量741.62
储存条件-20 °C 低温冷冻保存。
性质
Related Categories Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Core Bioreagents, N, NAD and Analogs, Nucleosides and Nucleotides, Nucleosides, Nucleotides, Oligonucleotides, Research Essentials
assay ≥95%
storage temp. −20°C
原产地美国
描述

Biochem/physiol Actions

Electron donor

Application

β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).

供货状态True
参考文献

Ying W., NAD+ and NADH in cellular functions and cell death. Front. Biosci. 11, 3129-3148, (2006)

Lin H., Nicotinamide adenine dinucleotide: beyond a redox coenzyme. Org. Biomolecular Chem. 5, 2541-2554, (2007)

Imai S., "Clocks" in the NAD World: NAD as a metabolic oscillator for the regulation of metabolism and aging. Biochim. Biophys. Acta 1804, 1584-1590, (2010)

Ebstein RP, Mankuta D, et al., Are retinoids potential therapeutic agents in disorders of social cognition including autism? FEBS Lett. 585, 1529-1536, (2011)

Hottiger MO., ADP-ribosylation of histones by ARTD1: an additional module of the histone code? FEBS Lett. 585, 1595-1599, (2011)

Grahnert A, Grahnert A, et al., Review: NAD +: a modulator of immune functions. Innate Immunity 17, 212-233, (2011)

Li X, Kazgan N., Mammalian sirtuins and energy metabolism. Int. J. Biol. Sci. 7, 575-587, (2011)

类型酶 & 辅酶
安全信息
符号 GHS07
信号词 Warning
危险声明 H315-H319-H335
警示性声明 P261-P305 + P351 + P338
危害码 Xi
风险声明 36/37/38
安全声明 26-36
WGK德国 3