中文名称英文名称CAS 编号规格所属品牌订货号
青霉素 G 钾盐Penicillin G potassium salt113-98-41MUSIGMAPENK
青霉素 G 钾盐Penicillin G potassium salt113-98-410MUSIGMAPENK
青霉素 G 钾盐Penicillin G potassium salt113-98-4100MUSIGMAPENK
品牌SIGMA
产品名称 青霉素 G 钾盐 : Penicillin G potassium salt ——【产品编号:SIGMA-PENK】
CAS编号113-98-4
别名青霉素钾盐,青霉素G钾盐,苄青霉素钾盐,Penicillin G Potas
级别科学级
纯度&分析~1600 U/mg
Tips一种常用的研究级抗生素类制品,适用于科学研究、辅料、规模化生产等。
分子式 C16H17KN2O4S
分子量372.48
储存条件常温避光保存。
性质
APPEARANCE WHITE TO OFF-WHITE POWDER
SOLUBILITY CLEAR COLORLESS TO LIGHT YELLOW SOLUTION AT 100MG/ML IN WATER
IR SPECTRUM CONSISTENT WITH STRUCTURE
MOISTURE CONTENT NOT MORE THAN 1.5%
POTENCY APPROX. 1,600UNITS PENICILLIN-G BASE PER MG
原产地美国
描述

Biochem/physiol Actions

Mode of Action: Inhibits bacterial cell wall synthesis.
Antimicrobial spectrum: Gram-positive bacteria

Penicillin G is active against gram-positive and gram-negative aerobic and anaerobic bacteria. Penicillin G inhibits cell wall synthesis by binding to penicillin binding proteins (PBPs) which inhibits peptidoglycan chain cross-lining. Penicillin G is stable against hydrolysis by β-lactamases, such as penicillinases and cephalosporinases.

Application

Penicillin G is a narrow spectrum antibiotic. It is the drug of choice for Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. Penicillin G potassium salt is used to study murosomes of staphylococci1 and the penicillin-induced lysis of Streptococcus mutans2.

供货状态True
参考文献

1. P Giesbrecht, T Kersten, et al., Fan-shaped ejections of regularly arranged murosomes involved in penicillin-induced death of Staphylococci. J. Bacteriol. 174, 2241-2252, (1992)

2. T A Kral and M D Callaway, Penicillin-induced lysis of Streptococcus mutans. Infect. Immun. 46, 442-447, (1984)

Merck 14,7094

Beil. 27,IV,5861

类型抗生素
安全信息
符号  GHS07
信号词  Warning
危险声明  H317
警示性声明  P280
个人防护装备  dust mask type N95 (US), Eyeshields, Faceshields, Gloves
危害码  Xn
风险声明  42/43
安全声明  36/37
WGK德国  2
RTECS  XH9700000