描述 | Application
酸性、碱性和中性药物 RP-HPLC 分离中的流动相改性剂。通过抑制拖尾提高氨基酸和氨基酸酰胺的 HPLC 分离度。
Triethylamine, a mobile-phase modifier in the RP-HPLC separation of acidic, basic and neutral molecules, improves the resolution of amino acids and amino acid amides by HPLC by suppressing tailing and the stability of drugs and other compounds.
Other Notes
Component of volatile buffer system in ion-exchange HPLC of oligonucleotides1
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参考文献 | 1. Use of a volatile buffer system in ion-exchange high-performance liquid chromatography of oligonucleotides. J.M. Munholland et al. Anal. Biochem. 178, 320, (1989)
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Development and Validation of RP-HPLC Method for Simultaneous Determination of Granisetron and Dexamethasone. Heda AA, Kathiriya JM, Gadade DD, Puranik PK. Indian J. Pharm. Sci. 73, 696-699, (2011)
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Stability indicating HPLC method for the simultaneous determination of moxifloxacin and prednisolone in pharmaceutical formulations. Razzaq SN, Khan IU, Mariam I, Razzaq SS. Chem. Cent. J. 6, 94, (2012)
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General reversed-phase high-performance liquid chromatographic method for the separation of drugs using triethylamine as a competing base. R.W. Roos, C.A. LauCam J. Chromatogr. A 370, 403, (1986)
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Determination of the enantiomers of alpha-amino acids and alpha-amino acid amides by high-performance liquid chromatography with a chiral mobile phase. A. Duchateau J. Chromatogr. A 461, 419, (1989)
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Stability-Indicating RP-HPLC Method for the Simultaneous Determination of Escitalopram Oxalate and Clonazepam. Kakde RB, Satone DD, Gadapayale KK, Kakde MG. J. Chromatogr. Sci., (2012)
High-throughput carotenoid profiling using multivariate curve resolution. Wehrens R, Carvalho E, Masuero D, et al. Anal. Bioanal. Chem, (2012)
Merck 14,9666
Beil. 4,IV,322
FT-IR 1 (1), 300:A / FT-NMR 1 (1), 481:B
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